Hydrazine hydrate (1:1) → 4-(2,4-dimethoxyphenyl)-7-methoxy-2H-phthalazin-1-one

Reaction equation

[CH3:1][O:2][C:3]1[CH:21]=[C:20]([O:22][CH3:23])[CH:19]=[CH:18][C:4]=1[C:5]([C:7]1[CH:15]=[CH:14][C:13]([O:16][CH3:17])=[CH:12][C:8]=1[C:9](O)=[O:10])=O.O.[NH2:25][NH2:26]>>[CH3:1][O:2][C:3]1[CH:21]=[C:20]([O:22][CH3:23])[CH:19]=[CH:18][C:4]=1[C:5]1[C:7]2[C:8](=[CH:12][C:13]([O:16][CH3:17])=[CH:14][CH:15]=2)[C:9](=[O:10])[NH:26][N:25]=1

Participants

Reactant 2

HCID 24654Hydrazine hydrate (1:1)

HCID 69213029HCID 69213029, compound

Product 1

HCID 692095074-(2,4-dimethoxyphenyl)-7-methoxy-2H-phthalazin-1-one

Procedure

This compound is obtained according to the procedure described in 1.2. by reacting 2-(2,4-dimethoxybenzoyl)-5-methoxybenzoic acid with hydrazine hydrate.

Workup

customThis compound is obtained

Sources & evidence

ORD record: ord-133f07169b0b4b9a9423d1d1f5a7dc44
Source dataset: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07423030B2

Reaction notes

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