Reaction equation
I[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[O:8][CH3:9].C([Li:14])CCC.CCCCCC>O1CCCC1>[CH3:9][O:8][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[Li:14]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
To a solution of 2-iodoanisole (4.97g, 21.24 mmol, Aldrich 98%) in anhydrous tetrahydrofuran (33 mL) at −78° C., was added a solution of n-butyllithium in hexane (2.5 M, 8.5 mL, 21.25 mmol, Aldrich). The reaction was stirred at −78 OC for 0.5-1 hr to give a solution of the 2-methoxyphenyl lithium for the following reaction.
Sources & evidence
- ORD record
- ord-2478b8791e0b46a197891a217f637021
- Source dataset
- uspto-grants-2008_09
- Patent number
- US07423051B2
Linked notes
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