Acetic Acid → Tert-butyl 4-(7-bromo-2-(4-sulfamoylphenylamino)quinazolin-8-yloxy)piperidine-1-carboxylate
Reaction equation
[Br:7][c:8]1[cH:9][cH:10][c:11]2[cH:12][n:13][c:14]([Cl:32])[n:15][c:16]2[c:17]1[O:18][CH:19]1[CH2:20][CH2:21][N:22]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:23][CH2:24]1.[C:44]([OH:45])(=[O:46])[CH3:47].[CH3:1][C:2]([CH3:3])([O-:4])[CH3:5].[CH:48]([OH:49])([CH3:50])[CH3:51].[K+:6].[NH2:33][c:34]1[cH:35][cH:36][c:37]([S:40]([NH2:41])(=[O:42])=[O:43])[cH:38][cH:39]1>>[Br:7][c:8]1[cH:9][cH:10][c:11]2[cH:12][n:13][c:14]([NH:33][c:34]3[cH:35][cH:36][c:37]([S:40]([NH2:41])(=[O:42])=[O:43])[cH:38][cH:39]3)[n:15][c:16]2[c:17]1[O:18][CH:19]1[CH2:20][CH2:21][N:22]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[CH2:23][CH2:24]1
