N,N-Dimethyl-1,3-propanediamine → P,P-bis(2,2-dimethyl-1-aziridinyl)-N-(3-dimethylaminopropyl)phosphinic amide

Reaction equation

[CH2:21]1[O:22][CH2:23][CH2:24][CH2:25]1.[CH3:14][N:15]([CH2:16][CH2:17][CH2:18][NH2:19])[CH3:20].[CH3:1][C:2]1([CH3:13])[N:3]([P:5](=[O:6])([N:7]2[C:8]([CH3:10])([CH3:11])[CH2:9]2)[Cl:12])[CH2:4]1>>[CH3:1][C:2]1([CH3:13])[N:3]([P:5](=[O:6])([N:7]2[C:8]([CH3:10])([CH3:11])[CH2:9]2)[NH:19][CH2:18][CH2:17][CH2:16][N:15]([CH3:14])[CH3:20])[CH2:4]1

Participants

Reactant 3

HCID 7993N,N-Dimethyl-1,3-propanediamine

HCID 8028Tetrahydrofuran

HCID 13511140P,P-bis(2,2-dimethyl-1-aziridinyl)phosphinyl chloride

Product 1

HCID 366242P,P-bis(2,2-dimethyl-1-aziridinyl)-N-(3-dimethylaminopropyl)phosphinic amide

Sources & evidence

ORD record: ord-d9d1756cfc5445ee9a92398ab5e1997c
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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