Toluene → Methyl 5-(4-quinolin-2-ylpiperazin-1-yl)hexanoate

HRID 304294

Reaction equation

HRID 304294 reaction equation
[CH3:38][c:39]1[cH:40][cH:41][cH:42][cH:43][cH:44]1.[N:11]1([c:17]2[n:18][c:19]3[cH:20][cH:21][cH:22][cH:23][c:24]3[cH:25][cH:26]2)[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]1.[O:1]=[C:2]([CH2:3][CH2:4][CH2:5][C:6](=[O:7])[O:8][CH3:9])[CH3:10].[c:27]1([CH3:28])[cH:29][cH:30][c:31]([S:32]([OH:33])(=[O:34])=[O:35])[cH:36][cH:37]1>>[CH:2]([CH2:3][CH2:4][CH2:5][C:6](=[O:7])[O:8][CH3:9])([CH3:10])[N:14]1[CH2:13][CH2:12][N:11]([c:17]2[n:18][c:19]3[cH:20][cH:21][cH:22][cH:23][c:24]3[cH:25][cH:26]2)[CH2:16][CH2:15]1

Participants

5

Reactant 4

HCID 1140TolueneHCID 5011QuipazineHCID 6101p-Toluenesulfonic acidHCID 84129Methyl 5-oxohexanoate

Product 1

HCID 23155655Methyl 5-(4-quinolin-2-ylpiperazin-1-yl)hexanoate

Sources & evidence

ORD record
ord-900a46878ac04e52b547a50bd7e4ec9d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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