Potassium Cation → 2-Fluoro-5-methoxypyridine

HRID 305141

Reaction equation

HRID 305141 reaction equation
[C:14](=[O:15])([O-:16])[O-:17].[CH3:26][CH2:27][O:28][CH2:29][CH3:30].[Cl:23][CH2:24][Cl:25].[F:1][c:2]1[cH:3][cH:4][c:5]([OH:8])[cH:6][n:7]1.[I:20][CH3:21].[K+:18].[K+:19].[O:9]=[CH:10][N:11]([CH3:12])[CH3:13].[OH2:22]>>[F:1][c:2]1[cH:3][cH:4][c:5]([O:8][CH3:10])[cH:6][n:7]1

Participants

9

Reactant 8

HCID 813Potassium Cation2×HCID 962WaterHCID 3283Diethyl EtherHCID 6228DimethylformamideHCID 6328Methyl iodideHCID 6344DichloromethaneHCID 19660Carbonate IonHCID 27631086-Fluoropyridin-3-ol

Product 1

HCID 189731092-Fluoro-5-methoxypyridine

Sources & evidence

ORD record
ord-22c5f9f8c0544745bf9a2eb1b27ca7cb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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