Potassium Cation → 7-(4-chlorophenyl)-2-((2-methoxy-6-(trifluoromethyl)pyridin-3-yl)methyl)-8-(pyridin-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

HRID 305598

Reaction equation

HRID 305598 reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9](-[c:18]3[cH:19][cH:20][n:21][cH:22][cH:23]3)[c:10]3[n:11]([cH:12][cH:13]2)[c:14](=[O:17])[nH:15][n:16]3)[cH:6][cH:7]1.[Cl:24][CH2:25][c:26]1[c:27]([O:36][CH3:37])[n:28][c:29]([C:32]([F:33])([F:34])[F:35])[cH:30][cH:31]1.[K+:38].[K+:39].[O-:40][C:41]([O-:42])=[O:43].[O:44]=[CH:45][N:46]([CH3:47])[CH3:48]>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[c:9](-[c:18]3[cH:19][cH:20][n:21][cH:22][cH:23]3)[c:10]3[n:11]([cH:12][cH:13]2)[c:14](=[O:17])[n:15]([CH2:25][c:26]2[c:27]([O:36][CH3:37])[n:28][c:29]([C:32]([F:33])([F:34])[F:35])[cH:30][cH:31]2)[n:16]3)[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 577993927-(4-chlorophenyl)-8-(pyridin-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-oneHCID 598348193-(Chloromethyl)-2-methoxy-6-(trifluoromethyl)pyridine

Product 1

HCID 160048077-(4-chlorophenyl)-2-((2-methoxy-6-(trifluoromethyl)pyridin-3-yl)methyl)-8-(pyridin-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one

Sources & evidence

ORD record
ord-73c31671b93d4c5cb695ced06d7168a7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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