Chloroform → 1-Benzyl-3-t-butyldimethylsilyloxymethylpyrrolidine

HRID 306304

Reaction equation

HRID 306304 reaction equation
[C:10]([CH3:11])([CH3:12])([CH3:13])[Si:14]([Cl:15])([CH3:16])[CH3:17].[CH2:18]([c:19]1[cH:20][cH:21][cH:22][cH:23][cH:24]1)[N:25]1[CH2:26][CH:27]([CH2:30][OH:31])[CH2:28][CH2:29]1.[CH:1]([N:2]([CH:3]([CH3:4])[CH3:5])[CH2:6][CH3:7])([CH3:8])[CH3:9].[CH:32]([Cl:33])([Cl:34])[Cl:35]>>[C:10]([CH3:11])([CH3:12])([CH3:13])[Si:14]([CH3:16])([CH3:17])[O:31][CH2:30][CH:27]1[CH2:26][N:25]([CH2:18][c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[CH2:29][CH2:28]1

Participants

5

Reactant 4

HCID 6212ChloroformHCID 28928tert-Butyldimethylsilyl chlorideHCID 81531DiisopropylethylamineHCID 5176654(1-Benzylpyrrolidin-3-yl)methanol

Product 1

HCID 199149271-Benzyl-3-t-butyldimethylsilyloxymethylpyrrolidine

Sources & evidence

ORD record
ord-32c60a0ee7684b4597c379430d0a6579
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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