Hydroxide → 3-Amino-2-fluorobenzoic acid

Reaction equation

[F:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][cH:8][cH:9][c:10]1[N+:11]([O-:12])=[O:13].[O:14]1[CH2:15][CH2:16][CH2:17][CH2:18]1.[OH-:19].[OH-:21].[Pd+2:20]>>[F:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][cH:8][cH:9][c:10]1[NH2:11]

Participants

Reactant 4

HCID 961Hydroxide2×

HCID 8028Tetrahydrofuran

HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)

HCID 186729922-Fluoro-3-nitrobenzoic acid

Product 1

HCID 230943433-Amino-2-fluorobenzoic acid

Sources & evidence

ORD record: ord-4973a1f19d6b40f0b3bb8495e0b247d1
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…