Sodium ion → 2-amino-6-(2,6-dichlorophenyl)-8-(4-methoxybenzyl)-8H-pyrido[2,3-d]pyrimidin-7-one

HRID 309805

Reaction equation

HRID 309805 reaction equation
[CH3:23][O:24][c:25]1[cH:26][cH:27][c:28]([CH2:29][Cl:30])[cH:31][cH:32]1.[CH3:34][N:35]([CH3:36])[CH:37]=[O:38].[H-:2].[NH2:3][c:4]1[n:5][cH:6][c:7]2[c:8]([n:9]1)[nH:10][c:11](=[O:22])[c:12](-[c:14]1[c:15]([Cl:21])[cH:16][cH:17][cH:18][c:19]1[Cl:20])[cH:13]2.[Na+:1].[OH2:33]>>[NH2:3][c:4]1[n:5][cH:6][c:7]2[c:8]([n:9]1)[n:10]([CH2:29][c:28]1[cH:27][cH:26][c:25]([O:24][CH3:23])[cH:32][cH:31]1)[c:11](=[O:22])[c:12](-[c:14]1[c:15]([Cl:21])[cH:16][cH:17][cH:18][c:19]1[Cl:20])[cH:13]2

Participants

7

Reactant 6

HCID 923Sodium ionHCID 962WaterHCID 6228DimethylformamideHCID 699934-Methyloxybenzyl chlorideHCID 166653HydrideHCID 104949152-Amino-6-(2,6-dichlorophenyl)-pyrido[2,3-d]pyrimidin-7-ol

Product 1

HCID 115970962-amino-6-(2,6-dichlorophenyl)-8-(4-methoxybenzyl)-8H-pyrido[2,3-d]pyrimidin-7-one

Sources & evidence

ORD record
ord-7b1ca32e6265417fb94dfc3b55e188eb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

Loading…