Imidazole → 1-Tert-butyl 2-methyl 4-((tert-butyldimethylsilyl)oxy)pyrrolidine-1,2-dicarboxylate

HRID 310444

Reaction equation

HRID 310444 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([C:14](=[O:15])[O:16][CH3:17])[CH2:10][CH:11]([OH:13])[CH2:12]1.[C:28]([CH3:29])([CH3:30])([CH3:31])[Si:32]([CH3:33])([CH3:34])[Cl:35].[O:18]=[CH:19][N:20]([CH3:21])[CH3:22].[nH:23]1[cH:24][cH:25][n:26][cH:27]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([C:14](=[O:15])[O:16][CH3:17])[CH2:10][CH:11]([O:13][Si:32]([C:28]([CH3:29])([CH3:30])[CH3:31])([CH3:33])[CH3:34])[CH2:12]1

Participants

5

Reactant 4

HCID 795ImidazoleHCID 6228DimethylformamideHCID 28928tert-Butyldimethylsilyl chlorideHCID 51482991-Tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate

Product 1

HCID 141170021-Tert-butyl 2-methyl 4-((tert-butyldimethylsilyl)oxy)pyrrolidine-1,2-dicarboxylate

Sources & evidence

ORD record
ord-64688a4879684f9a8d7329d272562eae
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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