Acetic Acid → 8-Chloro-7-fluoro-1-methyl-4-oxo-1,4-dihydrobenzo[b][1,8]naphthyridine-3-carboxylic acid

HRID 311663Notes

Reaction equation

HRID 311663 reaction equation
[CH3:24][C:25](=[O:26])[OH:27].[Cl:1][c:2]1[c:3]([F:23])[cH:4][c:5]2[c:6]([n:7][c:8]3[n:9]([CH3:21])[cH:10][c:11]([C:16](=[O:17])[O:18][CH2:19][CH3:20])[c:12](=[O:15])[c:13]3[cH:14]2)[cH:22]1.[ClH:28]>>[Cl:1][c:2]1[c:3]([F:23])[cH:4][c:5]2[c:6]([n:7][c:8]3[n:9]([CH3:21])[cH:10][c:11]([C:16](=[O:17])[OH:18])[c:12](=[O:15])[c:13]3[cH:14]2)[cH:22]1

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 313Hydrochloric AcidHCID 147005498-Chloro-3-ethoxycarbonyl-7-fluoro-1-methyl-4-oxo-1,4-dihydro-benzo[b][1,8]naphthyridine

Product 1

HCID 147005548-Chloro-7-fluoro-1-methyl-4-oxo-1,4-dihydrobenzo[b][1,8]naphthyridine-3-carboxylic acid

Sources & evidence

ORD record
ord-9659eea43300422d86fd8dccc9781fd2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Reaction notes

Loading…