Dichloromethane → 4-Bromomethyl-2-methoxy-biphenyl

Reaction equation

[CH3:9][O:10][c:11]1[c:12](-[c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[cH:13][cH:14][c:15]([CH2:17][OH:18])[cH:16]1.[Cl:44][CH2:45][Cl:46].[O:1]=[C:2]1[N:3]([Br:8])[C:4](=[O:5])[CH2:6][CH2:7]1.[c:25]1([P:26]([c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[c:33]2[cH:34][cH:35][cH:36][cH:37][cH:38]2)[cH:39][cH:40][cH:41][cH:42][cH:43]1>>[Br:8][CH2:17][c:15]1[cH:14][cH:13][c:12](-[c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[c:11]([O:10][CH3:9])[cH:16]1

Participants

Reactant 4

HCID 6344Dichloromethane

HCID 11776Triphenylphosphine

HCID 67184N-bromobutanimide

HCID 22997534(2-Methoxy-biphenyl-4-yl)-methanol

Product 1

HCID 229975474-Bromomethyl-2-methoxy-biphenyl

Sources & evidence

ORD record: ord-53150608af554f2c944876785528c26d
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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