Potassium Cation → 5-[3-[1-(difluoromethoxy)propan-2-yloxy]-5-[(5-methylpyrazin-2-yl)carbamoyl]phenoxy]-N,N-dimethylpyrazine-2-carboxamide

HRID 312854

Reaction equation

HRID 312854 reaction equation
[C:38](=[O:39])([O-:40])[O-:41].[CH3:44][CH2:45][O:46][C:47](=[O:48])[CH3:49].[CH3:50][C:51]#[N:52].[Cl:26][c:27]1[n:28][cH:29][c:30]([C:33](=[O:34])[N:35]([CH3:36])[CH3:37])[n:31][cH:32]1.[F:1][CH:2]([O:3][CH2:4][CH:5]([CH3:6])[O:7][c:8]1[cH:9][c:10]([C:11](=[O:12])[NH:13][c:14]2[n:15][cH:16][c:17]([CH3:20])[n:18][cH:19]2)[cH:21][c:22]([OH:24])[cH:23]1)[F:25].[K+:42].[K+:43]>>[F:1][CH:2]([O:3][CH2:4][CH:5]([CH3:6])[O:7][c:8]1[cH:9][c:10]([C:11](=[O:12])[NH:13][c:14]2[n:15][cH:16][c:17]([CH3:20])[n:18][cH:19]2)[cH:21][c:22]([O:24][c:27]2[n:28][cH:29][c:30]([C:33](=[O:34])[N:35]([CH3:36])[CH3:37])[n:31][cH:32]2)[cH:23]1)[F:25]

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 6342AcetonitrileHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 590004705-chloro-N,N-dimethylpyrazine-2-carboxamideHCID 674879143-[1-(difluoromethoxy)propan-2-yloxy]-5-hydroxy-N-(5-methylpyrazin-2-yl)benzamide

Product 1

HCID 1436605835-[3-[1-(difluoromethoxy)propan-2-yloxy]-5-[(5-methylpyrazin-2-yl)carbamoyl]phenoxy]-N,N-dimethylpyrazine-2-carboxamide

Sources & evidence

ORD record
ord-493f8f8341b34ff6a28c353e6b82eda9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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