Dichloromethane → 2-(3-bromo-4-methanesulfonyl-phenyl)-3-cyclopentyl-N-pyrazin-2-yl-propionamide

HRID 314008

Reaction equation

HRID 314008 reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH:12]([C:13](=[O:14])[OH:15])[CH2:16][CH:17]2[CH2:18][CH2:19][CH2:20][CH2:21]2)[cH:5][cH:6][c:7]1[S:8](=[O:9])(=[O:10])[CH3:11].[Br:41][N:42]1[C:43](=[O:44])[CH2:45][CH2:46][C:47]1=[O:48].[CH2:56]([Cl:57])[Cl:58].[NH2:49][c:50]1[n:51][cH:52][cH:53][n:54][cH:55]1.[c:22]1([P:23]([c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[cH:36][cH:37][cH:38][cH:39][cH:40]1>>[Br:1][c:2]1[cH:3][c:4]([CH:12]([C:13](=[O:15])[NH:49][c:50]2[n:51][cH:52][cH:53][n:54][cH:55]2)[CH2:16][CH:17]2[CH2:18][CH2:19][CH2:20][CH2:21]2)[cH:5][cH:6][c:7]1[S:8](=[O:9])(=[O:10])[CH3:11]

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 11776TriphenylphosphineHCID 67184N-bromobutanimideHCID 78747AminopyrazineHCID 120676662-(3-Bromo-4-methanesulfonyl-phenyl)-3-cyclopentyl-propionic acid

Product 1

HCID 223151242-(3-bromo-4-methanesulfonyl-phenyl)-3-cyclopentyl-N-pyrazin-2-yl-propionamide

Sources & evidence

ORD record
ord-8104f7e8cd31492c9e9b0303a3e1e708
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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