Tetrahydrofuran → 1-(4-Amino-2-chlorophenyl)ethanol

HRID 314458

Reaction equation

HRID 314458 reaction equation
[CH3:19][Si:20]([CH3:21])([CH3:22])[CH2:23][CH2:24][O:36][C:37]([NH:25][c:26]1[cH:27][c:28]([Cl:35])[c:29]([CH:32]([CH3:33])[OH:34])[cH:30][cH:31]1)=[O:38].[CH3:2][CH2:3][CH2:4][CH2:5][N+:6]([CH2:7][CH2:8][CH2:9][CH3:10])([CH2:11][CH2:12][CH2:13][CH3:14])[CH2:15][CH2:16][CH2:17][CH3:18].[F-:1].[O:39]1[CH2:40][CH2:41][CH2:42][CH2:43]1>>[NH2:25][c:26]1[cH:27][c:28]([Cl:35])[c:29]([CH:32]([CH3:33])[OH:34])[cH:30][cH:31]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 54096646[3-Chloro-4-(1-hydroxy-ethyl)-phenyl]carbamic acid 2-trimethylsilanyl-ethyl ester

Product 1

HCID 185436011-(4-Amino-2-chlorophenyl)ethanol

Sources & evidence

ORD record
ord-ffa1654794ac458d8c6b1a4de9d85a7f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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