Dichloromethane → 2-(3-Piperidin-4-ylmethyl-[1,2,4]oxadiazol-5-yl)furo[3,2-c]pyridine

HRID 314901

Reaction equation

HRID 314901 reaction equation
[C:8]([O:9][C:10](=[O:11])[N:15]1[CH2:16][CH2:17][CH:18]([CH2:21][c:22]2[n:23][o:24][c:25](-[c:27]3[cH:28][c:29]4[cH:30][n:31][cH:32][cH:33][c:34]4[o:35]3)[n:26]2)[CH2:19][CH2:20]1)([CH3:12])([CH3:13])[CH3:14].[Cl:36][CH2:37][Cl:38].[F:1][C:2]([F:3])([F:4])[C:5]([OH:6])=[O:7]>>[NH:15]1[CH2:16][CH2:17][CH:18]([CH2:21][c:22]2[n:23][o:24][c:25](-[c:27]3[cH:28][c:29]4[cH:30][n:31][cH:32][cH:33][c:34]4[o:35]3)[n:26]2)[CH2:19][CH2:20]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 576595624-(5-Furo[3,2-c]pyridin-2-yl-[1,2,4]oxadiazol-3-ylmethyl)piperidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 116305842-(3-Piperidin-4-ylmethyl-[1,2,4]oxadiazol-5-yl)furo[3,2-c]pyridine

Sources & evidence

ORD record
ord-e014b523a51f469bac7a034a5af3f799
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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