Triethylamine → 3-cyano-N-(4-dimethylaminomethyl-benzyl)-benzamide

HRID 31500

Reaction equation

HRID 31500 reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[CH:12]=[CH:11][C:8]([CH2:9][NH2:10])=[CH:7][CH:6]=1)[CH3:3].[C:13]([C:15]1[CH:16]=[C:17]([CH:21]=[CH:22][CH:23]=1)[C:18](Cl)=[O:19])#[N:14].C(N(CC)CC)C>C(Cl)Cl>[C:13]([C:15]1[CH:16]=[C:17]([CH:21]=[CH:22][CH:23]=1)[C:18]([NH:10][CH2:9][C:8]1[CH:7]=[CH:6][C:5]([CH2:4][N:2]([CH3:1])[CH3:3])=[CH:12][CH:11]=1)=[O:19])#[N:14]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 1937144-DimethylaminomethylbenzylamineHCID 3084833-Cyanobenzoyl chloride

Product 1

HCID 95374593-cyano-N-(4-dimethylaminomethyl-benzyl)-benzamide

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Prepared analogously to Example 9d from 4-dimethylaminomethyl-benzylamine, 3-cyanobenzoylchloride and triethylamine in methylene chloride.

Sources & evidence

ORD record
ord-48a9cad839ea4f30ba1f392f4e85295e
Source dataset
uspto-grants-2008_09
Patent number
US07425641B2

Linked notes

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