Sodium Bicarbonate → HCID 178498471, compound

HRID 31529

Reaction equation

HRID 31529 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([C:9]([OH:11])=[O:10])[NH:7][N:8]=1)([O-:3])=[O:2].[C:12](=O)(O)[O-].[Na+]>CO.S(=O)(=O)(O)O>[CH3:12][O:10][C:9]([C:6]1[NH:7][N:8]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=1)=[O:11]

Participants

4

Reactant 2

HCID 516892Sodium BicarbonateHCID 178524578HCID 178524578, compound

Product 1

HCID 178498471HCID 178498471, compound

Reagents, catalysts & solvents 1

HCID 18363649Sulfuric acid methanolSolvent

Procedure

A solution of 5-Nitro-2H-pyrazole-3-carboxylic acid (5 gm, 32 mmol) in 100 ml of 2% sulfuric acid methanol was refluxed for 20 hours. The mixture was cooled to room temperature and added to saturated sodium bicarbonate. The mixture was extracted with ethyl acetate three times to obtain 3.59 gm of title product after drying over magnesium sulfate, filtering and evaporating to dryness. ESI M+1=171.

Workup

  1. extractionThe mixture was extracted with ethyl acetate three times

Sources & evidence

ORD record
ord-22a35fe448e645d49e111277870338bb
Source dataset
uspto-grants-2008_09
Patent number
US07425640B2

Linked notes

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