Water → 2-Acetyl-4-(4-pyridyl)cyclohexanone

Reaction equation

[C:26]([CH3:27])(=[O:28])[c:29]1[nH:30][cH:31][cH:32][n:33]1.[CH2:8]([Li:9])[CH2:10][CH2:11][CH3:12].[CH3:39][CH2:40][CH2:41][CH2:42][CH2:43][CH3:44].[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[O:34]1[CH2:35][CH2:36][CH2:37][CH2:38]1.[OH2:45].[n:13]1[cH:14][cH:15][c:16]([CH:19]2[CH2:20][CH2:21][C:22](=[O:25])[CH2:23][CH2:24]2)[cH:17][cH:18]1>>[n:13]1[cH:14][cH:15][c:16]([CH:19]2[CH2:20][CH:21]([C:26]([CH3:27])=[O:28])[C:22](=[O:25])[CH2:23][CH2:24]2)[cH:17][cH:18]1

Participants

Reactant 7

HCID 962Water

HCID 7912Diisopropylamine

HCID 8028Tetrahydrofuran

HCID 8058Hexane

HCID 5389722-Acetylimidazole

HCID 10154273Cyclohexanone, 4-(4-pyridinyl)-

HCID 178418339Butyllithium

Product 1

Sources & evidence

ORD record: ord-4e31c32bf99d4526bfe0187b45dad4bf
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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