Water → 5-Bromo-4-chloro-6-(trifluoromethyl)pyrimidine

Reaction equation

[Br:1][c:2]1[c:3]([OH:12])[n:4][cH:5][n:6][c:7]1[C:8]([F:9])([F:10])[F:11].[CH:19]([Cl:20])([Cl:21])[Cl:22].[OH2:18].[P:13]([Cl:14])([Cl:15])([Cl:16])=[O:17]>>[Br:1][c:2]1[c:3]([Cl:15])[n:4][cH:5][n:6][c:7]1[C:8]([F:9])([F:10])[F:11]

Participants

Reactant 4

HCID 962Water

HCID 6212Chloroform

HCID 24813Phosphorus oxychloride

HCID 178518144CID 11299507

Product 1

HCID 115362505-Bromo-4-chloro-6-(trifluoromethyl)pyrimidine

Sources & evidence

ORD record: ord-304e16cdbeec4839a7eafe3b64bbe4dc
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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