Sodium Ion → 4-(4-Fluorophenyl)-2,6-dimethyl-5-pyrimidinemethanol

Reaction equation

[Cl:28][CH2:29][Cl:30].[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]([CH3:20])[n:11][c:12]([CH3:19])[c:13]2[C:14](=[O:15])[O:16][CH2:17][CH3:18])[cH:6][cH:7]1.[Na+:21].[Na+:22].[O-:23][S:24](=[O:25])(=[O:26])[O-:27]>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]([CH3:20])[n:11][c:12]([CH3:19])[c:13]2[CH2:14][OH:15])[cH:6][cH:7]1

Participants

Reactant 4

HCID 923Sodium Ion2×

HCID 1117Sulfate Ion

HCID 6344Dichloromethane

HCID 14513884Ethyl 4-(4-fluorophenyl)-2,6-dimethyl-5-pyrimidinecarboxylate

Product 1

HCID 145138854-(4-Fluorophenyl)-2,6-dimethyl-5-pyrimidinemethanol

Sources & evidence

ORD record: ord-523a4b69a2684109b3eb640546f3eb8c
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (8/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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