Dichloromethane → 3-chloro-N-[3-(2'-oxospiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-1'(2'H)-yl)propyl]thiophene-2-carboxamide

HRID 318802

Reaction equation

HRID 318802 reaction equation
[CH3:26][CH2:27][N:28]([CH2:29][CH3:30])[CH2:31][CH3:32].[Cl:33][c:34]1[c:35]([C:39](=[O:40])[Cl:41])[s:36][cH:37][cH:38]1.[Cl:42][CH2:43][Cl:44].[NH2:1][CH2:2][CH2:3][CH2:4][N:5]1[C:6](=[O:25])[C:7]2([CH2:8][O:9][c:10]3[c:11]2[cH:12][c:13]2[c:14]([cH:18]3)[O:15][CH2:16][O:17]2)[c:19]2[cH:20][cH:21][cH:22][cH:23][c:24]21>>[NH:1]([CH2:2][CH2:3][CH2:4][N:5]1[C:6](=[O:25])[C:7]2([CH2:8][O:9][c:10]3[c:11]2[cH:12][c:13]2[c:14]([cH:18]3)[O:15][CH2:16][O:17]2)[c:19]2[cH:20][cH:21][cH:22][cH:23][c:24]21)[C:39]([c:35]1[c:34]([Cl:33])[cH:38][cH:37][s:36]1)=[O:40]

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8471TriethylamineHCID 27358243-Chlorothiophene-2-carbonyl chlorideHCID 119998911'-(3-aminopropyl)spiro[furo[2,3-f]-[1,3]benzodioxole-7,3'-indol]-2'(1'H)-one

Product 1

HCID 592634603-chloro-N-[3-(2'-oxospiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-1'(2'H)-yl)propyl]thiophene-2-carboxamide

Sources & evidence

ORD record
ord-e8e33bf9d2fb4d17b490b8af674e8da9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (8/10)

Linked notes

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