1-(4,4-Dimethylcyclohex-1-enyl)-2-nitrobenzene → 2-(4,4-Dimethylcyclohexyl)aniline
Reaction equation
[CH3:1][C:2]1([CH3:17])[CH2:7][CH2:6][C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[N+:14]([O-])=O)=[CH:4][CH2:3]1>[Pd].C(OCC)(=O)C>[CH3:1][C:2]1([CH3:17])[CH2:7][CH2:6][CH:5]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=2[NH2:14])[CH2:4][CH2:3]1Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Procedure
A mixture of 1-(4,4-dimethylcyclohex-1-enyl)-2-nitrobenzene (16.3 g, 70.5 mmol) prepared in Example (3a), 10% palladium on carbon (1 g, wet) and ethyl acetate (100 mL) was stirred for 14 hours and 30 minutes under a hydrogen atmosphere at atmospheric pressure and room temperature.
Sources & evidence
- ORD record
- ord-10fe35a6694f4bad8e1553d8d6b3a1f6
- Source dataset
- uspto-grants-2008_09
- Patent number
- US07425554B2
Reaction notes
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