Methyl 3-cyano-2-phenylpropanoate → 2-Pyrrolidinone, 3-phenyl-

HRID 323293

Reaction equation

HRID 323293 reaction equation

[C:1]([CH2:3][CH:4]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[C:5](OC)=[O:6])#[N:2]>C(OCC)(=O)C>[C:9]1([CH:4]2[CH2:3][CH2:1][NH:2][C:5]2=[O:6])[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

Participants

3

Reactant 1

HCID 18464584Methyl 3-cyano-2-phenylpropanoate

Product 1

HCID 2017892-Pyrrolidinone, 3-phenyl-

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

Prepare by the method of Example 2.2.2 using methyl 3-cyano-2-phenylpropionate to give the title compound Rf=0.20 (silica gel, ethyl acetate).

Sources & evidence

ORD record: ord-3c66997508ce4426884bd00d0def4208
Source dataset: uspto-grants-2001_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06211199B1

Linked notes

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