Hydrochloric Acid → 2-Acetylthio-3-methylbenzoic acid
Reaction equation
[SH:1][C:2]1[C:10]([CH3:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].[C:12](OC(=O)C)(=[O:14])[CH3:13].Cl>C(O)(=O)C>[C:12]([S:1][C:2]1[C:10]([CH3:11])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5])(=[O:14])[CH3:13]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
2-Mercapto-3-methylbenzoic acid (9.0 g, 54 mmol), acetic anhydride (6.5 g, 63 mmol) and glacial acetic acid (25 ml) were refluxed 1 hour, then poured into dilute hydrochloric acid. The product was filtered and recrystallized from toluene.
Workup
- filtrationThe product was filtered
- customrecrystallized from toluene
Sources & evidence
- ORD record
- ord-6715ab2fd23843db950559761faa08af
- Source dataset
- uspto-grants-1984_04
- Patent number
- US04440941
Reaction notes
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