2-ethylhexanoic acid tin(II) salt → p-Dioxanone 2,5-Morpholinedione
Reaction equation
[O:1]1[CH2:6][CH2:5][O:4][CH2:3][C:2]1=[O:7].[NH:8]1[C:13](=[O:14])[CH2:12][O:11][C:10](=[O:15])[CH2:9]1.CCCCC(C([O-])=O)CC.CCCCC(C([O-])=O)CC.[Sn+2]>C1(C)C=CC=CC=1>[O:1]1[CH2:6][CH2:5][O:4][CH2:3][C:2]1=[O:7].[NH:8]1[C:13](=[O:14])[CH2:12][O:11][C:10](=[O:15])[CH2:9]1Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
p-Dioxanone (4.0 g, 0.039 moles), 2,5-morpholinedione (0.5 g, 0.0043 moles) and a catalytic amount of stannous octoate (0.22 ml of a 0.0132 M toluene solution, 0.0000029 moles) are heated and magnetically mixed in a flame and vacuum dried, sealed glass ampoule according to the following temperature/time scheme:
Workup
- additionmagnetically mixed in
- temperaturea flame
- customvacuum dried
- customsealed glass ampoule
Sources & evidence
- ORD record
- ord-95e8c813bc214fd5962dbfdcd92da48d
- Source dataset
- uspto-grants-1984_04
- Patent number
- US04441496
Reaction notes
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