1,2-Epoxybutane → 1-(p-Ethylphenoxy)-butan-2-ol

Participants

Reaction Steps

In a closed vessel 12.2g (0.1 mol) of p-ethylphenol, 7.2 g (0.1 mol) of 1,2-butylene oxide and 0.8 ml of a 50% aqueous solution of sodium hydroxide were heated at 140° to 145° C for 4 hours in the same way as in Example 1. The reaction mixture obtained was treated in the same way as in Example 1 to afford 14.8 g of 1-(p-ethylphenoxy)-butan-2-ol (compound No. 52) in a yield of 76.3%.

Provenance & Evidence