4-Aminobenzoic Acid → L-Isoleucine

Reaction equation

[NH2:1][C@H:2]([C:7]([OH:9])=[O:8])[CH2:3][CH2:4]SC.[CH:10]1C(C(O)=O)=CC=C(N)[CH:11]=1.N[C@H](C(O)=O)CC1C=CC=CC=1.N1CCC[C@H]1C(O)=O>>[NH2:1][C@H:2]([C:7]([OH:9])=[O:8])[C@H:3]([CH2:10][CH3:11])[CH3:4]

Participants

Reactant 4

HCID 9784-Aminobenzoic Acid

HCID 6137L-Methionine

HCID 6140L-Phenylalanine

HCID 145742L-Proline

Product 1

HCID 6306L-Isoleucine

Procedure

L-methionine 2 g; PABA 0.2 g; L-phenylalanine 2 g; L-proline 2 g;

Sources & evidence

ORD record: ord-fc104d766ccb45e191f276fee5749e22
Source dataset: uspto-grants-2008_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07429449B2

Reaction notes

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