Benzaldehyde → 1-(3-(5-Methyl-1h-imidazol-1-yl)propyl)-5-phenylimidazolidine-2,4-dione
Reaction equation
[CH3:1][C:2]1[N:6]([CH2:7][CH2:8][CH2:9][NH2:10])[CH:5]=[N:4][CH:3]=1.[CH:11](=[O:18])C1C=CC=CC=1.[CH2:19]([N+]#[C-])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1.[O:28]([C:30]#[N:31])[K]>>[CH3:1][C:2]1[N:6]([CH2:7][CH2:8][CH2:9][N:10]2[CH:19]([C:20]3[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=3)[C:30](=[O:28])[NH:31][C:11]2=[O:18])[CH:5]=[N:4][CH:3]=1Participants
5
Procedure
The compound was synthesized starting from (3-(5-methyl-1H-imidazol-1-yl)propyl)amine 0.278 g (2 mmol), benzaldehyde 0.202 ml (2 mmol), benzylisonitrile 0.245 ml (2 mmol) pyridiniumchloride 0.231 g (2 mmol) and KOCN 0.165 g (2 mmol) as described in method 1.