4-Isopropylaniline → (4-Isopropylphenyl)[4-(trifluoromethoxy)benzyl]amine

HRID 33774

Reaction equation

HRID 33774 reaction equation
[F:1][C:2]([F:13])([F:12])[O:3][C:4]1[CH:11]=[CH:10][C:7]([CH:8]=O)=[CH:6][CH:5]=1.[CH:14]([C:17]1[CH:23]=[CH:22][C:20]([NH2:21])=[CH:19][CH:18]=1)([CH3:16])[CH3:15]>>[CH:14]([C:17]1[CH:23]=[CH:22][C:20]([NH:21][CH2:8][C:7]2[CH:10]=[CH:11][C:4]([O:3][C:2]([F:13])([F:12])[F:1])=[CH:5][CH:6]=2)=[CH:19][CH:18]=1)([CH3:16])[CH3:15]

Participants

3

Reactant 2

HCID 74644-IsopropylanilineHCID 69573p-(Trifluoromethoxy)benzaldehyde

Product 1

HCID 59797515(4-Isopropylphenyl)[4-(trifluoromethoxy)benzyl]amine

Procedure

Following the procedure described in Example 1A, step 1, 4-(trifluoromethoxy)benzaldehyde and 4-isopropylaniline gave the title compound as a colorless oil.

Sources & evidence

ORD record
ord-ce2ff44b7d8648bdae8a132a82ecdd80
Source dataset
uspto-grants-2008_09
Patent number
US07429666B2

Linked notes

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