2-Naphthalenecarboxaldehyde → (3-Fluoropyridin-4-yl)-(naphthalen-2-yl)-methanol

HRID 34005

Reaction equation

HRID 34005 reaction equation
[F:1][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][CH:7]=1.[CH:8]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[CH:11]=[CH:10][C:9]=1[CH:18]=[O:19]>>[F:1][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][C:7]=1[CH:18]([C:9]1[CH:10]=[CH:11][C:12]2[C:17](=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH:8]=1)[OH:19]

Participants

3

Reactant 2

HCID 62012-NaphthalenecarboxaldehydeHCID 677943-Fluoropyridine

Product 1

HCID 23070144(3-Fluoropyridin-4-yl)-(naphthalen-2-yl)-methanol

Procedure

Using 5.2 mL of 3-fluoropyridine and 10.2 g of 2-naphthaldehyde as starting materials, 17.0 g of the title compound was obtained as a colorless powder in the same manner as described in Production example 18.

Sources & evidence

ORD record
ord-489381524fa944d5bab72f8cdee78306
Source dataset
uspto-grants-2008_09
Patent number
US07429609B2

Linked notes

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