Basic information
- CAS
372-47-4- Standard SMILES
Fc1cccnc1- InChIKey
CELKOWQJPVJKIL-UHFFFAOYSA-N- Molecular formula
- C5H4FN
- Average molar mass
- 97.09 g/mol
- Monoisotopic mass
- 97.03277735
Names & identifiers
- Preferred name
- 3-Fluoropyridine
- IUPAC
- 3-fluoropyridine
- English name
- 3-Fluoropyridine
- Molecular formula
- C5H4FN
- Molecular weight
- 97.09
Names & synonyms
3-Fluoropyridine372-47-4Pyridine, 3-fluoro-CCRIS 1717NSC 5078EINECS 206-755-4DTXSID10190688RefChem:93977Pyridine, 3-fluoro-(8CI)DTXCID50113179Pyridine, 3-fluoro-(8CI)(9CI)206-755-4
Show more names
2503-Floro-pyridine3-Fluoroypyridine3-Fluoropyridine>Pyridine, 3-fluoro-3-Fluoropyridine 98%3-Fluoropyridine,98%3-Fluoropyridine,99%3-Fluoropyridine, 99% 1GR
CELKOWQJPVJKIL-UHFFFAOYSA-NInChI=1/C5H4FN/c6-5-2-1-3-7-4-5/h1-4MFCD00006374AP9KGY2VWZNSC-50783-fluropyridine3-fluoro-pyridineUNII-AP9KGY2VWZ
Database identifiers
- CAS
372-47-4- PubChem CID
- 67794
- DTXSID
DTXSID10190688- ChEMBL
CHEMBL1162361- UNII
- AP9KGY2VWZ
- EC Number
- 206-755-4
- Nikkaji
- J150.742G
Properties
Computed structural properties
- XLogP
- 0.8
- Topological polar surface area
- 12.9 Ų
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 2
- Rotatable bonds
- 0
- Heavy atoms
- 7
- Formal charge
- 0
- Complexity
- 56
Experimental & physicochemical properties
SpringerMaterials PropertiesCoriolis coupling
Physicochemical properties
- Melting point
- 251 · 251-254°C (dec.)
- Boiling point
- 107 · 107-108 °C (lit.)
- Density
- 1.13 g/mL · 1.13 g/mL at 25 °C (lit.)
- refractive index
- 20 · n20/D 1.472(lit.)
- Flash point
- 56 °F · 56 °F
- storage temp.
- Inert atmosphere,Room Temperature
- form
- Liquid
- pka
- 1 · pK1:2.97(+1) (25°C)
- Specific Gravity
- 1.13 · 1.130
- color
- Clear yellow
- BRN
- 105702 · 105702
- InChI
- InChI=1S/C5H4FN/c6-5-2-1-3-7-4-5/h1-4H
- InChIKey
- CELKOWQJPVJKIL-UHFFFAOYSA-N
- SMILES
- C1=NC=CC=C1F
- CAS DataBase Reference
- 372 · 372-47-4(CAS DataBase Reference)
- FDA UNII
- 9 KGY2VWZ · AP9KGY2VWZ
- NIST Chemistry Reference
- 3 · 3-F-pyridine(372-47-4)
- UNSPSC Code
- 12352100 · 12352100
- NACRES
- 22 · NA.22
- Symbol(GHS)
- 2 · GHS02,GHS07
- Signal word
- Danger
- Hazard statements
- 225 · H225-H315-H319-H335
- Precautionary statements
- 210 · P210-P302+P352-P305+P351+P338
- target organs
- Respiratory system
- PPE
- Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
- Hazard Codes
- F,Xi,Xn
- Risk Statements
- 11 · 11-36/37/38-20/21/22
- Safety Statements
- 16 · 16-26-36/37/39-33-7/9
- RIDADR
- 1993 · UN 1993 3/PG 2
- WGK Germany
- 3 · 3
- Hazard Note
- Flammable/Irritant
- HazardClass
- 3 · 3
- PackingGroup
- II
- HS Code
- 29333990 · 29333990
- Storage Class
- 3 · 3 - Flammable liquids
- Hazard Classifications
- 2 Flam · Eye Irrit. 2Flam. Liq. 2Skin Irrit. 2STOT SE 3
- Limited Quantities
- 1 L · 1.0 L (0.3 gallon) (liquid)
- Excepted Quantities
- Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
Safety & regulation
GHS classification
GHS Classification
Danger
H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]
P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 61 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Hazard information
Hazard Classes and CategoriesFlam. Liq. 2 (100%)
Safety data
- PPE
- Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
- wgk
- 3
- ridadr
- UN 1993 3/PG 2
- hs_code
- 29333990
- risk_code
- 11-36/37/38-20/21/22
- Signal word
- Danger
- Symbol(GHS)
- GHS02,GHS07
- hazard_code
- F,Xi,Xn
- hazard_note
- Flammable/Irritant
- safety_code
- 16-26-36/37/39-33-7/9
- hazard_class
- 3
- Storage Class
- 3 - Flammable liquids
- packing_group
- II
- target organs
- Respiratory system
- Hazard statements
- H225-H315-H319-H335
- Limited Quantities
- 1.0 L (0.3 gallon) (liquid)
- Excepted Quantities
- Max Inner Pack (30g or 30ml) and Max Outer Pack (500g or 500ml)
- Hazard Classifications
- Eye Irrit. 2Flam. Liq. 2Skin Irrit. 2STOT SE 3
- Precautionary statements
- P210-P302+P352-P305+P351+P338
Chemistry & industry
Applications
Uses3-Fluoropyridine was used in the synthesis of 3-halopyridin-4-yl-boronic acids and esters.
General Description3-Fluoropyridine is oxidized to corresponding N-oxides, which on treatment with hot acetic anhydride and hydrolysis yields 3-halo-2-pyridones. Microwave spectrum of 3-fluoropyridine has been investigated in the frequency range of 8-18GHz at dry ice temperature. Deprotonation of 3-fluoropyridine with Bu3MgLi in THF at -10°C has been studied.
Preparation methods
PreparationA combination of CsF and HF provides a very reactive fluoride source and has shown faint promise with 3-chloropyridine giving 3-fluoropyridine in a very low yield.
Upstream & downstream products
Upstream raw materials
Downstream products
Suppliers100 total
国药集团化学试剂有限公司86-21-63210123 · [email protected]
北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
INTATRADE GmbH+49 3493/605464 · [email protected]
上海赫文斯化工有限公司15721252604 17321035817 · [email protected]
韶远科技（上海）有限公司021-50795510 4000665055 · [email protected]
科瑞迪化学400-821-5857 021-64326257 · [email protected]
Syntechem Co.,Ltd[email protected]
上海迈瑞尔生化科技有限公司4006356688 18621169109 · [email protected]
北京华威锐科化工有限公司0757-86329057 18934348241 · [email protected]
河北松辰医药科技有限公司0319-5801333-8008 15630992918 · [email protected]
阿法埃莎（中国）化学有限公司400-6106006 · [email protected]
太原市瑞和丰科贸有限公司+86 351 7031519 · [email protected]
安耐吉化学&3A（安徽泽升科技股份有限公司）400-0056266 · [email protected]
石家庄斯迪亚诺精细化工有限公司0311-89250318 13582355795 · [email protected]
武汉凯威斯科技有限公司86-027-67849912 · [email protected]
艾琪康医药科技（上海）有限公司13661411401 · [email protected]
阜新四维卤化物有限公司0418-2260776 · [email protected]
上海瀚鸿科技股份有限公司021-54306202 13764082696 · [email protected]
上海相辉医药科技有限公司13761987713 · [email protected]
上海景颜化工科技有限公司13817811078 · [email protected]
嘉兴市艾森化工有限公司0573-85285100 18627885956 · [email protected]
Pure Chemistry Scientific Inc.001-857-928-2050 or 1-888-588-9418 · [email protected]
上海盛雄生物科技发展有限公司86-021-64960112 13774219177 · [email protected]
上海隆盛化工有限公司58099637 13585536065 · [email protected]
孝感深远化工有限公司15527621225; 15527621225 · [email protected]
四川库利南科技有限公司400-1166-196 18981987031 · [email protected]
天津希恩思生化科技有限公司400 638 7771 · [email protected]
河南多贝化工有限公司0370-2785118 17550508557 · [email protected]
天津津御达化工科技有限公司022-58013646 13011382049 · [email protected]
上海思域化工科技有限公司86-21-34053660 · [email protected]
苏州思变化学技术有限公司0512-65617459 18915409046 · [email protected]
赛默飞世尔科技（中国）有限公司800-810-5118 · [email protected]
北京伊诺凯科技有限公司400-810-7969 010-59572699 · [email protected]
上海健超生物科技有限公司150-2103-5486 18017383231 · [email protected]
TCI AMERICA800-4238616 · [email protected]
TOKYO CHEMICAL INDUSTRY CO., LTD.03-36680489 · [email protected]
TCI Europe320-37350700 · [email protected]
卡迪亚医药科技有限公司0371-86615086 18203638366 0371-86159066 13526786601
越林试剂021-62960152 · [email protected]
Clearsynth Labs Limited+91-22-26355700 · [email protected]
无锡中坤生化科技有限公司+86 0510-85629785
上海皋翔化工有限公司021-57816257 18930243658 · [email protected]
上海洪创医药科技有限公司18151128828 · [email protected]
苏州爱玛特生物科技有限公司0512-56316828 4008675858 · [email protected]
北京环宇世纪化学科技有限公司hysj_bj.com
上海湄水化工科技有限公司021-60549325 18616193163
上海将来实业股份有限公司400-0066400 13621662912 · [email protected]
上海将来实业股份有限公司021-61552785 · [email protected]
Related reactions
70 records
Compound notes
Loading…