Trifluoroacetic acid → 4'-[(2-n-Butylthio-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylic acid
Reaction equation
[CH2:1]([S:5][C:6]1[N:10]([CH2:11][C:12]2[CH:17]=[CH:16][C:15]([C:18]3[C:19]([C:24]([O:26]C(C)(C)C)=[O:25])=[CH:20][CH:21]=[CH:22][CH:23]=3)=[CH:14][CH:13]=2)[C:9]2[CH:31]=[CH:32][CH:33]=[CH:34][C:8]=2[N:7]=1)[CH2:2][CH2:3][CH3:4].FC(F)(F)C(O)=O>>[CH2:1]([S:5][C:6]1[N:10]([CH2:11][C:12]2[CH:17]=[CH:16][C:15]([C:18]3[C:19]([C:24]([OH:26])=[O:25])=[CH:20][CH:21]=[CH:22][CH:23]=3)=[CH:14][CH:13]=2)[C:9]2[CH:31]=[CH:32][CH:33]=[CH:34][C:8]=2[N:7]=1)[CH2:2][CH2:3][CH3:4]Participants
3
Procedure
Prepared in analogous manner to Example 9 from tert.butyl 4'-[(2-n-butylthio-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate and trifluoroacetic acid.
Sources & evidence
- ORD record
- ord-489ea8bfae3d484b80c926d5f7ba51d6
- Source dataset
- uspto-grants-1999_01