1-Methylpiperazine → 1-(3,7,11,15-Tetramethyl-2,6,10,14-hexadecatetraenoyl)-4-methylpiperazine

HRID 34567

Reaction equation

[CH3:1][C:2]([CH2:7][CH2:8][CH:9]=[C:10]([CH3:22])[CH2:11][CH2:12][CH:13]=[C:14]([CH3:21])[CH2:15][CH2:16][CH:17]=[C:18]([CH3:20])[CH3:19])=[CH:3][C:4]([OH:6])=O.[CH3:23][N:24]1[CH2:29][CH2:28][NH:27][CH2:26][CH2:25]1>>[CH3:1][C:2]([CH2:7][CH2:8][CH:9]=[C:10]([CH3:22])[CH2:11][CH2:12][CH:13]=[C:14]([CH3:21])[CH2:15][CH2:16][CH:17]=[C:18]([CH3:20])[CH3:19])=[CH:3][C:4]([N:27]1[CH2:28][CH2:29][N:24]([CH3:23])[CH2:25][CH2:26]1)=[O:6]

Participants

Reactant 2

HCID 531671-Methylpiperazine

HCID 1285703,7,11,15-Tetramethyl-2,6,10,14-hexadecatetraenic acid

Product 1

HCID 543831271-(3,7,11,15-Tetramethyl-2,6,10,14-hexadecatetraenoyl)-4-methylpiperazineYield 90%

Procedure

The procedure of Example 9 was repeated except that 6.1 g of 3,7,11,15-tetramethyl-2,6,10,14-hexadecatetraenoic acid and 3.3 ml of 1-methylpiperazine were used as starting materials. 6.9 g (yield 90%) of the title compound was obtained as a colorless oil.

Sources & evidence

ORD record: ord-8b1f21b0a524415082373ce0bab68411
Source dataset: uspto-grants-1988_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04762829

Linked notes

Loading…