Ethylparaben → Ethyl-4-(diethylaminoethyloxy)benzoate

Reaction equation

[CH2:1]([O:3][C:4](=[O:12])[C:5]1[CH:10]=[CH:9][C:8]([OH:11])=[CH:7][CH:6]=1)[CH3:2].[CH2:13]([N:15]([CH2:19][CH3:20])[CH2:16][CH2:17]Cl)[CH3:14]>>[CH2:1]([O:3][C:4](=[O:12])[C:5]1[CH:10]=[CH:9][C:8]([O:11][CH2:14][CH2:13][N:15]([CH2:19][CH3:20])[CH2:16][CH3:17])=[CH:7][CH:6]=1)[CH3:2]

Participants

Reactant 2

HCID 8434Ethylparaben

HCID 13364Diethylaminoethyl chloride

Product 1

HCID 410618Ethyl-4-(diethylaminoethyloxy)benzoate

Procedure

The title compound was prepared by alkylation of ethyl-4-hydroxybenzoate with diethylchloroethylamine using methods analogous to those described in Example 2(i).

Sources & evidence

ORD record: ord-8a375f9364754a1dafcfffb19361445c
Source dataset: uspto-grants-2007_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07173061B2

Reaction notes

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