Tributylamine → 3,3,3-Trifluoro-2-(trifluoromethyl)-1-propene

Temperature

65 °C

In a four necked 100 ml flask equipped with a condenser, a dropping funnel and a thermometer, tributylamine (20.0 g, 108 mmoles) was charged and warmed to 65° C. Monochloromethyl 2-trifluoromethyl-3,3,3-trifluoropropanoate (4.88 g, 20 mmol) was dropwise added thereto while stirring. The reaction was continued at the same temperature as above for 3 hours while stirring. The gas evolved from a top of the condenser was washed with an alkaline solution, dried with alumina and cooled. The resultant liquid was distilled to give 2-trifluoromethyl-3,3,3-trifluoropropene (2.49 g). Yield, 76 %.

1. customIn a four necked 100 ml flask equipped with a condenser, a dropping funnel
2. customwas continued at the same temperature as above for 3 hours
3. stirringwhile stirring
4. washwas washed with an alkaline solution
5. customdried with alumina
6. temperaturecooled
7. distillationThe resultant liquid was distilled

ORD record

ord-d57e115760924d43a21fc3df3125c5f3

Source dataset

uspto-grants-1988_08

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US04766238