1-Phenylethanol → (1-Chloroethyl)benzene

HRID 354264

Reaction equation

HRID 354264 reaction equation
[C:1]1([CH:7](O)[CH3:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.N1C(Cl)=NC(Cl)=NC=1[Cl:12]>>[Cl:12][CH:7]([C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)[CH3:8]

Participants

3

Reactant 2

HCID 74091-PhenylethanolHCID 7954Cyanuric chloride

Product 1

HCID 12648(1-Chloroethyl)benzene

Procedure

Using a procedure analogous to that of Example 1, 100 g (0.82 mol) of 1-phenylethane-1-ol is reacted with 97.6 g (0.529 mol) of cyanuric chloride over a period of 14 hours at a reaction temperature of 90° C. After phase separation, treatment with sodium hydroxide and purification by distillation, 1-chloro-1-phenylethane having a purity of>99% and containing<0.3% of isomeric alkyl chlorides is obtained.

Workup

  1. customAfter phase separation, treatment
  2. customwith sodium hydroxide and purification
  3. distillationby distillation, 1-chloro-1-phenylethane having a purity of>99%
  4. additioncontaining<0.3% of isomeric alkyl chlorides
  5. customis obtained

Sources & evidence

ORD record
ord-06b8f1e0727a4317a83d8d61e641fccb
Source dataset
uspto-grants-2004_06
Patent number
US06756513B2

Linked notes

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