N,N'-Diethylthiourea → HCID 20506556, compound

HRID 354911

Reaction equation

HRID 354911 reaction equation
[CH2:1]([NH:3][C:4]([NH:6][CH2:7][CH3:8])=[S:5])[CH3:2].[Br:9][CH2:10][C:11](=[O:25])[CH:12]([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>CC(C)=O>[BrH:9].[C:13]1([CH:12]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:11]2([OH:25])[CH2:10][S:5][C:4](=[N:3][CH2:1][CH3:2])[N:6]2[CH2:7][CH3:8])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

4

Reactant 2

HCID 2735009N,N'-DiethylthioureaHCID 27946353-Bromo-1,1-diphenylacetone

Product 1

HCID 20506556HCID 20506556, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent2×

Procedure

To a filtered solution of 1.32 g. of 1,3-diethyl-2-thiourea in 25 ml. of acetone is added a filtered solution of 3-bromo-1,1-diphenyl-2-propanone in 25 ml. of acetone. The mixture is allowed to stand, then the solid is collected by filtration, washed with acetone and dried in vacuo, giving 3.73 g. of the desired product, m.p. 174°-176° C. (dec.).

Workup

  1. filtrationthe solid is collected by filtration
  2. washwashed with acetone
  3. customdried in vacuo
  4. customgiving 3.73 g

Sources & evidence

ORD record
ord-2827049d555644459acdb2003933a016
Source dataset
uspto-grants-1983_03
Patent number
US04377589

Linked notes

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