HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → 11-(2-Oxo-3-phenyl-benzimidazolin-1-yl)-undecanoic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 2H-Benzimidazol-2-one, 1,3-dihydro-1-phenyl- | HCID 84657 | — |
| Reactant | Methyl 11-bromoundecanoate | HCID 223913 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 11-(2-Oxo-3-phenyl-benzimidazolin-1-yl)-undecanoic acid methyl ester | HCID 12961187 | — |
Reaction Steps
The product is produced as described in example 1 from 1.3 g. of NaH (80% suspension in mineral oil), 10 g. of 1-phenylbenzimidazolin-2-one, 200 cc. of DMF, 13.3 g. of 11-bromoundecanoic acid methyl ester and 1.3 g. of NaJ. Eluant in chromatographic purification: hexane/ethylacetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04377695 |
| Source dataset | uspto-grants-1983_03 |
| ORD ID | ord-133a1494065746b1ad3399c84cba163e |
| Source note | uspto-grants-1983_03 |