3-Methyl-1-butene → 5-Hydroxy-2-methyl-6,6,6-trifluoro-5-trifluoromethylhex-2-ene

HRID 355186

Reaction equation

HRID 355186 reaction equation
[F:1][C:2]([F:10])([F:9])[C:3]([C:5]([F:8])([F:7])[F:6])=[O:4].[CH3:11][CH:12]([CH3:15])[CH:13]=[CH2:14]>>[OH:4][C:3]([C:5]([F:8])([F:7])[F:6])([C:2]([F:10])([F:9])[F:1])[CH2:14][CH:13]=[C:12]([CH3:15])[CH3:11]

Participants

3

Reactant 2

HCID 112393-Methyl-1-buteneHCID 12695Hexafluoroacetone

Product 1

HCID 127834375-Hydroxy-2-methyl-6,6,6-trifluoro-5-trifluoromethylhex-2-ene

Conditions

Temperature
125 °C

Procedure

A stirred mixture of hexafluoroacetone (235 g) and 3-methylbut-1-ene (100 g) was heated at 125° C. under a pressure of 17 atmospheres for a period of 20 hours. Distillation of the product mixture under reduced pressure yielded 5-hydroxy-2-methyl-6,6,6-trifluoro-5-trifluoromethylhex-2-ene as a mobile colourless liquid, b.p. 43° C./15 mm Hg.

Workup

  1. distillationDistillation of the product mixture under reduced pressure

Sources & evidence

ORD record
ord-65cee0cebf8e4d50ac625714b60261fb
Source dataset
uspto-grants-1983_03
Patent number
US04378316

Linked notes

Loading…