6-Bromoindole → 6-Bromo-2,3-dihydro-1H-indole

HRID 356043

Reaction equation

[Br:1][C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[CH:7][NH:8]2)=[CH:4][CH:3]=1.C([BH3-])#N.[Na+]>>[Br:1][C:2]1[CH:10]=[C:9]2[C:5]([CH2:6][CH2:7][NH:8]2)=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 6764936-Bromoindole

HCID 5003444Sodium cyanoborohydride

Product 1

HCID 130983796-Bromo-2,3-dihydro-1H-indole

Procedure

6-Bromoindole (D75) was reduced with sodium cyanoborohydride as in the method of Description 10 to yield the title compound (D76).

Sources & evidence

ORD record: ord-5363e505388d41b1bebffb2fc5907904
Source dataset: uspto-grants-1998_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05834494

Linked notes

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