Epichlorohydrin → Isostearyl glycidyl ether

Temperature

50 °C

Into a round bottom flask having a capacity of 1 liter and equipped with a reflux condenser, a thermometer, a dropping funnel, and a stirring means, 120 g of a 50% sodium hydroxide solution (60 g (1.5 mole) as pure sodium hydroxide), 68 g (0.25 mole) of isostearyl alcohol [5,7,7-trimethyl-2-(1,3,3-trimethylbutyl) octanol], 200 ml of n-hexane, and 2.51 g (0.0075 mole) of stearyl trimethyl ammonium chloride, were introduced in this order. The reaction mixture was kept at a reaction temperature of 25° C. in a water bath, and while vigorously stirring the mixture at a stirring speed of 400 r.p.m., 93 g (1 mole) of epichlorohydrin was added dropwise from the dropping funnel. It took about 1.5 hours for the addition of the epichlorohydrin, and the reaction mixture was heated to 50° C. and stirred for about 8 hours at this temperature. After the completion of the reaction, the mixture was treated in a usual manner, whereupon 67.9 g (yield: 83%) of isostearyl glycidyl ether (5,7,7-trimethyl-2-(1,3,3-trimethylbutyl)-octyl glycidyl ether) was obtained.

1. customInto a round bottom flask having
2. customa capacity of 1 liter and equipped with a reflux condenser
3. customThe reaction mixture was kept at a reaction temperature of 25° C. in a water bath
4. customAfter the completion of the reaction

ORD record

ord-f627163b3e1b4da8aeca592dd6510e85

Source dataset

uspto-grants-1984_08

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US04465869