Benzoic Acid → 2-[2-(N-methylformamido)phenyl]-2-oxoethyl benzoate

Reaction equation

Cl[CH2:2][C:3]([C:5]1[CH:14]=[CH:13][CH:12]=[CH:11][C:6]=1[N:7]([CH3:10])[CH:8]=[O:9])=[O:4].[C:15]([OH:23])(=[O:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[C:15]([O:23][CH2:2][C:3]([C:5]1[CH:14]=[CH:13][CH:12]=[CH:11][C:6]=1[N:7]([CH3:10])[CH:8]=[O:9])=[O:4])(=[O:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

Reactant 2

HCID 243Benzoic Acid

HCID 23128087N-[2-(Chloroacetyl)phenyl]-N-methylformamide

Product 1

HCID 867446442-[2-(N-methylformamido)phenyl]-2-oxoethyl benzoate

Procedure

The solution of 2'-(2-chloroacetyl)-N-methylformanilide may be reacted with benzoic acid by a method analogous to that of Example 2(d) to give the novel compound 2-[2-(N-methylformamido)phenyl]-2oxoethyl benzoate.

Sources & evidence

ORD record: ord-80df63b322f14c23b9824b05157b9bb0
Source dataset: uspto-grants-1991_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04997840

Reaction notes

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