Potassium Carbonate → 145544-79-2

HRID 358970

Reaction equation

HRID 358970 reaction equation
[N:1]1([CH2:6][CH:7]2[C:12]3[N:13]=[CH:14][NH:15][C:11]=3[CH2:10][CH2:9][NH:8]2)[CH2:5][CH2:4][CH2:3][CH2:2]1.C(=O)([O-])[O-].[K+].[K+].[Cl:22][C:23]1[CH:24]=[C:25]([CH2:30][C:31](Cl)=[O:32])[CH:26]=[CH:27][C:28]=1[Cl:29]>C(Cl)(Cl)Cl>[N:1]1([CH2:6][CH:7]2[C:12]3[N:13]=[CH:14][NH:15][C:11]=3[CH2:10][CH2:9][N:8]2[C:31](=[O:32])[CH2:30][C:25]2[CH:26]=[CH:27][C:28]([Cl:29])=[C:23]([Cl:22])[CH:24]=2)[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 27581492-(3,4-Dichlorophenyl)acetyl chlorideHCID 200656974-(Pyrrolidin-1-yl)methyl-4,5,6,7-tetrahydroimidazo[4,5-c]pyridine

Product 1

HCID 10000638145544-79-2

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

Prepared as Example No. 12, from 900 mg (4.37 mmoles) of 4-(pyrrolidin-1-yl)methyl-4,5,6,7-tetrahydroimidazo[4,5-c]pyridine, 950 mg (6.88 mmoles) of anhydrous potassium carbonate and 1.30 g (5.80 mmoles) of 3,4-dichlorophenylacetyl chloride in 35 ml of dry chloroform.

Sources & evidence

ORD record
ord-d1934ed4ebf3427e8197c3d0825c7e9b
Source dataset
uspto-grants-1991_03
Patent number
US04999359

Linked notes

Loading…