Phenol → 2-Isopropylphenol
Reaction equation
C1(O)C=CC=CC=1.[CH:8]([C:11]1[CH:16]=[CH:15][CH:14]=[C:13](C(C)C)[C:12]=1[OH:20])([CH3:10])[CH3:9]>[O-]C1C=CC=CC=1.[Al+3].[O-]C1C=CC=CC=1.[O-]C1C=CC=CC=1>[CH:8]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=1[OH:20])([CH3:10])[CH3:9]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
For example, U.S. Pat. No. 2,831,898 discloses a process for producing 2,6-diisopropyl phenol from propylene gas and phenol by Friedel-Crafts reaction at high pressure of 21-35 atm, high temperature of 200°-210° C. and under nitrogen atmosphere with aluminum phenoxide, as a catalyst, prepared from alumina and phenol. But there is a defect that 2,6-diisopropyl phenol desired was obtained only with 11.3% yield even though 2-isopropyl phenol which is a by-product was obtained with 31.4% yield.