1-Indanol → Indene

Reaction equation

[CH:1]1(O)[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH2:2]1.P([O-])([O-])([O-])=O.[Al+3]>>[CH2:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:3]=[CH:2]1

Participants

Reactant 2

HCID 228191-Indanol

HCID 64655Aluminum Phosphate

Product 1

HCID 7219IndeneYield 91.8%

Procedure

To a 25 ml one-neck round bottom flask are added 1-indanol (10 g, 75 mmol) and aluminum phosphate (ALPO4, 1.0 g, 8.2 mmol). The contents of the flask are heated under partial vacuum (5-10 mm Hg) to distill over indene and water. The water is removed by pipette, with the last traces being removed by drying over anhydrous magnesium sulfate to give indene (8 g) in an isolated yield of 92 mole percent.

Workup

temperatureThe contents of the flask are heated under partial vacuum (5-10 mm Hg)
distillationto distill over indene and water
customThe water is removed by pipette, with the last traces
custombeing removed
dry with materialby drying over anhydrous magnesium sulfate

Sources & evidence

ORD record: ord-a982bb2edb894c5b8a8ffea19d4a0a2b
Source dataset: uspto-grants-1995_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05414173

Reaction notes

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