HCID 3544471, compound → 2-(1-methyl-1H-pyrazol-4-yl)aniline
Reaction equation
[CH3:1][N:2]1[CH:6]=[C:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2[N+:13]([O-])=O)[CH:4]=[N:3]1>Cl>[CH3:1][N:2]1[CH:6]=[C:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=2[NH2:13])[CH:4]=[N:3]1Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
By the procedure of Example 3, 25 g of 1-methyl-4-(2-nitrophenyl)-1H-pyrazole prepared in Example 17 was reacted with 81.2 g of stannous chloride dihydrate in 200 ml concentrated HCl at reflux for 1 hour to yield, after similar work up, 18 g of the title compound as an oil.
Workup
- temperatureat reflux for 1 hour
- customto yield
Sources & evidence
- ORD record
- ord-994349ee057a41469515eab621dd6356
- Source dataset
- uspto-grants-1986_08
- Patent number
- US04606755
Reaction notes
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