Piperidine → 3-piperidin-1-ylbenzonitrile
Reaction equation
F[C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[C:5]#[N:6].[NH:10]1[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]1>>[N:10]1([C:2]2[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=2)[C:5]#[N:6])[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]1Participants
3
Procedure
According to a similar manner to that in Reference Example 17, the title compound was synthesized from 3-fluorobenzonitrile and piperidine.
Sources & evidence
- ORD record
- ord-5184a0893b5a47e8a32eabdc116304b7
- Source dataset
- uspto-grants-2000_10
- Patent number
- US06127541
Reaction notes
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