Reaction equation
[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[CH:3]=[CH:2]1.N1C=CC=CC=1.[Na]>O>[OH:1][C:5]1[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=1[C:3]#[CH:2]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
In the process described in Bull. Chem. Soc. Japan 29, 470-1(1956), benzofuran is heat-refluxed in the presence of pyridine and metallic sodium and thereafter treated with water to obtain 2-hydroxyphenylacetylene in 54% yield.
Sources & evidence
- ORD record
- ord-4583fc4ca99148e2b79a6e400394a2f8
- Source dataset
- uspto-grants-2000_10
- Patent number
- US06127583
Linked notes
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